PRA Health Sciences offers a range of pain models to assess pain perception and the efficacy of experimental analgesics in healthy volunteers and patient populations. PRA has been involved in conducting Phase I-IV studies in healthy volunteers and patients with various types of acute and chronic pain. Our Early Development Services (EDS) group has state-of-the-art Phase I facilities and equipment, as well as a broad expertise in pain studies and availability of a large network of pain specialists.
First-in-Human Drug Evaluation at PRA Health Sciences & The Revised EMA Guideline on Early Clinical Trials
In July 2017, the European Medicines Agency (EMA) published its revised guidance on first-in-human (FIH) and early clinical trials. The revision…
Oral Abuse Potential of Benzhydrocodone, a Novel Prodrug of Hydrocodone
Hydrocodone bitartrate (HB) and acetaminophen (APAP) combination products are known to be abused via oral, intranasal, and intravenous…